Sensitive nerve endings7/22/2023 ![]() For instance, a light tap on a painful area would result in intense pain. It represents increased sensitivity to pain. Hyperalgesia: An intensified reaction to a stimulus, which is normally painful.For instance, light stroking the skin would cause extremely unpleasant sensation. Allodynia: Pain due to a stimulus, which normally does not provoke pain.What are the other symptoms of neuropathic pain? Tend to respond to traditional painkillers such as: May respond to antidepressant or anti-epileptic medication such as: Tend not to respond to simple painkillers. This may be perceived as electric shock or shooting pain. If the cut is deep enough such that the median nerve is also cut, the nerve damage will result in pain signals being transmitted via the nerve to the brain. The pain fibres then send signals to the brain that is perceived as a sharp pain (nociceptive pain). When a person cuts his/her wrist, the tiny nerve endings at the wound are activated as a result of local tissue damage. Neuropathic pain and nociceptive pain may overlap or coexist following a nerve injury. It is distinguished from the common type of pain ( nociceptive pain) that is caused by a cut, burn or injury. Neuropathic pain is pain due to irritation of the nerves themselves. However distinction is made between two major types of physical pains due to their differing clinical behaviours. ![]() Ultimately all physical pains, as perceived by our brains, are mediated by nerves. Pain can be physical, psychological or both in origin. Without pain as a protective mechanism, humans may be exposed to harms and dangers that could ultimately threaten the existence of our species! However pain is distressing and if severe, can be debilitating.
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